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Posts: 29
Reply with quote  #1 
Its been a while since I posted/asked a question so here is a little context to my question:

I had mild Rosacea for years and have been using Skin Actives for more than 10 years. A couple of years ago my Rosacea started to worsen and I would get tiny papules and my skin became extremely dry (note this coincided with me entering into my 40s).

As my rosacea worsened, I was living out of the country without easy/good access to a dermatologist. I returned to the US and was able to see a dermatologist 9 months ago. As a result, I started using Metro gel and have had some moderate improvement with the papules and redness but the improvement is not consistent. But my biggest issue remains the extreme dryness and my usual SA moisturizing formulas no longer seem to help with the dryness.

ELS works great and I use that on days I work from home, but when I'm traveling or going into the office its too oily.

So my goal now is to experiment a little with my moisturizing regime to see if I can enhance the moisturizing capacity and support redness reduction.

Here is my list (note I've used these actives before with no bad side affects except for those starred) and I've included questions at the end of my list:

Canvas cream with EGF
Hyaluronic Acid
Glycerince or Sodium PCA
Beta Glucan*
ROS Terminator*


1. Glycerine vs. Sodium PCA: is one better than the other for my purposes?
2. ROS Terminator vs. Glutathione: is one better than the other for my purposes?
3. I tend to use a Canvas-Based cream containing EGF, Palmitoyl Pentapeptide 3, Matrixyl, HA and the antioxidant booster during the day . Should I back off of using any of these actives? I have not noticed they irritate my skin.



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Posts: 15,879
Reply with quote  #2 
Please have a look at my post of today in the blog. To make it easier for you, here it is:

Rosacea update 2018

New scientific evidence has shown that rosacea’s diverse features may be part of a progression of inflammation, which initially may not be visible to the naked eye but can be detected by looking at the changes in the anatomy, physiology and biochemistry of the skin. It starts with the common presentations of flushing and then stable face redness, and then it may progress to include papules and pustules, and potentially lead to development of external nodules and swellings called phymas.

Research on rosacea has intensified over the last 15 years and it suggests that there will be no simple answers. It seems that, underlying rosacea there is a complex system of disease-causing pathways that include defects in the immune system. Scientific progress in the elucidation of the mechanisms underlying rosacea will continue, but for the time being (and in the near future) there are no easy solutions and rosacea can only be controlled, and not “cured”.

What can you do for yourself?
I know this answer can be annoying for the sufferer of any chronic condition: try to avoid the triggers. The triggers for rosacea are various and changing with time for each person, and many are unavoidable during daily life. Try to avoid hot, crowded spaces, especially if there is cigarette smoke.

What can Skin Actives do for you?
Taking into account the complex causes of rosacea, you can try the following products that address one or more of the factors know to affect rosacea. We hope one or more of these products will help you.

1) Ameliorate inflammation using our anti-inflammatory cream.
2) control redox stress by using our antioxidant serum or antioxidant cream
3) use our rosacea control serum containing epidermal growth factor
4) see if our Celestite spritz (anti-aging hydromist) helps prevent flushing as a response to heat or smoke stress
5) ELS, our “every lipid serum” will help with skin dryness and accelerate recovery

Gallo, Richard L., Granstein, Richard D., Kang, Sewon, Mannis, Mark, Steinhoff, Martin, (Tan, Jerry, Thiboutot, Diane. (2018) Standard classification and pathophysiology of rosacea: The 2017 update by the National Rosacea Society Expert Committee. J. American Acad. Dermatology, 78: 148-155

Holmes, Anna D., Spoendlin, Julia, Chien, Anna L., Baldwin, Hilary, Chang, Anne Lynn S. (2018) Evidence-based update on rosacea comorbidities and their common physiologic pathways J. American Acad. Dermatology, 78: 156-166


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Posts: 15,879
Reply with quote  #3 
Incidentally, ROS* terminator contains glutathione.
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